Gene-specific Copy Number Variation Probe-FDPS
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Catalog: |
CNVFP-FDPS-05273 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FDPS). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
FDPS Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FDPS genes. This product achieves the purpose of detection by hybridizing with the FDPS gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Farnesyl Diphosphate Synthase |
Gene Summary [Provided by RefSeq] |
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008] |
Gene Symbol |
FDPS |
Location |
1q22 |
Chromosome |
Chromosome1 |
Coordinates |
This gene maps to 155278538-155290457 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-FDPS-05273-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-FDPS-05273-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-FDPS-05273-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-FDPS-05273-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-FDPS-05273-AQ |
467nm |
418nm |
|
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