Gene-specific Copy Number Variation Probe-FBXW7
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| Catalog: |
CNVFP-FBXW7-05266 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FBXW7). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
FBXW7 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FBXW7 genes. This product achieves the purpose of detection by hybridizing with the FBXW7 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
F-box And WD Repeat Domain Containing 7 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] |
| Gene Symbol |
FBXW7 |
| Location |
4q31.3 |
| Chromosome |
Chromosome4 |
| Coordinates |
This gene maps to 153242409-153456172 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-FBXW7-05266-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-FBXW7-05266-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-FBXW7-05266-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-FBXW7-05266-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-FBXW7-05266-AQ |
467nm |
418nm |
|
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