Gene-specific Copy Number Variation Probe-FBXW4
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Catalog: |
CNVFP-FBXW4-05269 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FBXW4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
FBXW4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FBXW4 genes. This product achieves the purpose of detection by hybridizing with the FBXW4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
F-box And WD Repeat Domain Containing 4 |
Gene Summary [Provided by RefSeq] |
This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22. [provided by RefSeq, Jul 2008] |
Gene Symbol |
FBXW4 |
Location |
10q24.32 |
Chromosome |
Chromosome10 |
Coordinates |
This gene maps to 103370420-103454743 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-FBXW4-05269-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-FBXW4-05269-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-FBXW4-05269-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-FBXW4-05269-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-FBXW4-05269-AQ |
467nm |
418nm |
|
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