Gene-specific Copy Number Variation Probe-FAS
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| Catalog: |
CNVFP-FAS-05364 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (FAS). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
FAS Gene-specific copy number variation probes are mainly used to detect the copy number variation related to FAS genes. This product achieves the purpose of detection by hybridizing with the FAS gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Fas Cell Surface Death Receptor |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011] |
| Gene Symbol |
FAS |
| Location |
10q23.31 |
| Chromosome |
Chromosome10 |
| Coordinates |
This gene maps to 90750287-90775542 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-FAS-05364-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-FAS-05364-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-FAS-05364-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-FAS-05364-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-FAS-05364-AQ |
467nm |
418nm |
|
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