Gene-specific Copy Number Variation Probe-F8
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Catalog: |
CNVFP-F8-04925 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (F8). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
F8 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to F8 genes. This product achieves the purpose of detection by hybridizing with the F8 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Coagulation Factor VIII |
Gene Summary [Provided by RefSeq] |
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008] |
Gene Symbol |
F8 |
Location |
Xq28 |
Chromosome |
ChromosomeX |
Coordinates |
This gene maps to 154064063-154250998 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-F8-04925-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-F8-04925-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-F8-04925-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-F8-04925-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-F8-04925-AQ |
467nm |
418nm |
|
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