Gene-specific Copy Number Variation Probe-ESRRG
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| Catalog: |
CNVFP-ESRRG-04715 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ESRRG). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ESRRG Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ESRRG genes. This product achieves the purpose of detection by hybridizing with the ESRRG gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Estrogen Related Receptor Gamma |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011] |
| Gene Symbol |
ESRRG |
| Location |
1q41 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 216676587-217311097 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ESRRG-04715-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ESRRG-04715-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ESRRG-04715-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ESRRG-04715-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ESRRG-04715-AQ |
467nm |
418nm |
|
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