Gene-specific Copy Number Variation Probe-ESPL1
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| Catalog: |
CNVFP-ESPL1-04725 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ESPL1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ESPL1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ESPL1 genes. This product achieves the purpose of detection by hybridizing with the ESPL1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Extra Spindle Pole Bodies Like 1, Separase |
| Gene Summary [Provided by RefSeq] |
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010] |
| Gene Symbol |
ESPL1 |
| Location |
12q13.13 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 53662082-53687427 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ESPL1-04725-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ESPL1-04725-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ESPL1-04725-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ESPL1-04725-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ESPL1-04725-AQ |
467nm |
418nm |
|
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