Gene-specific Copy Number Variation Probe-ERCC1
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| Catalog: |
CNVFP-ERCC1-04690 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ERCC1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ERCC1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ERCC1 genes. This product achieves the purpose of detection by hybridizing with the ERCC1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
ERCC Excision Repair 1, Endonuclease Non-catalytic Subunit |
| Gene Summary [Provided by RefSeq] |
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009] |
| Gene Symbol |
ERCC1 |
| Location |
19q13.32 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 45910590-45927177 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ERCC1-04690-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ERCC1-04690-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ERCC1-04690-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ERCC1-04690-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ERCC1-04690-AQ |
467nm |
418nm |
|
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