Gene-specific Copy Number Variation Probe-ERBB3
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| Catalog: |
CNVFP-ERBB3-04694 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ERBB3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ERBB3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ERBB3 genes. This product achieves the purpose of detection by hybridizing with the ERBB3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Erb-b2 Receptor Tyrosine Kinase 3 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
ERBB3 |
| Location |
12q13.2 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 56473808-56497291 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ERBB3-04694-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ERBB3-04694-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ERBB3-04694-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ERBB3-04694-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ERBB3-04694-AQ |
467nm |
418nm |
|
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