Gene-specific Copy Number Variation Probe-ELANE
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| Catalog: |
CNVFP-ELANE-04348 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ELANE). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ELANE Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ELANE genes. This product achieves the purpose of detection by hybridizing with the ELANE gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Elastase, Neutrophil Expressed |
| Gene Summary [Provided by RefSeq] |
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. [provided by RefSeq, Jan 2016] |
| Gene Symbol |
ELANE |
| Location |
19p13.3 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 852290-856246 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ELANE-04348-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ELANE-04348-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ELANE-04348-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ELANE-04348-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ELANE-04348-AQ |
467nm |
418nm |
|
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