Gene-specific Copy Number Variation Probe-E2F4
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| Catalog: |
CNVFP-E2F4-04233 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (E2F4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
E2F4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to E2F4 genes. This product achieves the purpose of detection by hybridizing with the E2F4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
E2F Transcription Factor 4 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
E2F4 |
| Location |
16q22.1 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 67226067-67232821 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-E2F4-04233-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-E2F4-04233-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-E2F4-04233-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-E2F4-04233-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-E2F4-04233-AQ |
467nm |
418nm |
|
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