Gene-specific Copy Number Variation Probe-DYRK1A
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Catalog: |
CNVFP-DYRK1A-04245 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DYRK1A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
DYRK1A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DYRK1A genes. This product achieves the purpose of detection by hybridizing with the DYRK1A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A |
Gene Summary [Provided by RefSeq] |
This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008] |
Gene Symbol |
DYRK1A |
Location |
21q22.13 |
Chromosome |
Chromosome21 |
Coordinates |
This gene maps to 38739858-38887679 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-DYRK1A-04245-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-DYRK1A-04245-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-DYRK1A-04245-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-DYRK1A-04245-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-DYRK1A-04245-AQ |
467nm |
418nm |
|
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