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Gene-specific Copy Number Variation Probe-DYRK1A

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Catalog: CNVFP-DYRK1A-04245
Classification: Copy Number Variation
Description: Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DYRK1A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services.
Application: DYRK1A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DYRK1A genes. This product achieves the purpose of detection by hybridizing with the DYRK1A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH.
Category: Copy Number Variation
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A
Gene Summary [Provided by RefSeq] This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol DYRK1A
Location 21q22.13
Chromosome Chromosome21
Coordinates This gene maps to 38739858-38887679 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 OR CNVFP-DYRK1A-04245-OR 573nm 548nm
2 RE CNVFP-DYRK1A-04245-RE 599nm 580nm
3 GO CNVFP-DYRK1A-04245-GO 551nm 525nm
4 GR CNVFP-DYRK1A-04245-GR 515nm 491nm
5 AQ CNVFP-DYRK1A-04245-AQ 467nm 418nm

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