Gene-specific Copy Number Variation Probe-DUSP8
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Catalog: |
CNVFP-DUSP8-04276 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DUSP8). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
DUSP8 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DUSP8 genes. This product achieves the purpose of detection by hybridizing with the DUSP8 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Dual Specificity Phosphatase 8 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008] |
Gene Symbol |
DUSP8 |
Location |
11p15.5 |
Chromosome |
Chromosome11 |
Coordinates |
This gene maps to 1575280-1593150 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-DUSP8-04276-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-DUSP8-04276-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-DUSP8-04276-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-DUSP8-04276-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-DUSP8-04276-AQ |
467nm |
418nm |
|
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