Gene-specific Copy Number Variation Probe-DUOXA1
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| Catalog: |
CNVFP-DUOXA1-04300 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DUOXA1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
DUOXA1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DUOXA1 genes. This product achieves the purpose of detection by hybridizing with the DUOXA1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Dual Oxidase Maturation Factor 1 |
| Gene Summary [Provided by RefSeq] |
Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013] |
| Gene Symbol |
DUOXA1 |
| Location |
15q21.1 |
| Chromosome |
Chromosome15 |
| Coordinates |
This gene maps to 45409685-45422057 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-DUOXA1-04300-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-DUOXA1-04300-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-DUOXA1-04300-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-DUOXA1-04300-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-DUOXA1-04300-AQ |
467nm |
418nm |
|
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