Gene-specific Copy Number Variation Probe-DOCK3
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| Catalog: |
CNVFP-DOCK3-04123 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DOCK3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
DOCK3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DOCK3 genes. This product achieves the purpose of detection by hybridizing with the DOCK3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Dedicator Of Cytokinesis 3 |
| Gene Summary [Provided by RefSeq] |
This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity, and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment of the WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficit hyperactivity disorder-like phenotype by a complex chromosomal rearrangement. [provided by RefSeq, Aug 2010] |
| Gene Symbol |
DOCK3 |
| Location |
3p21.2 |
| Chromosome |
Chromosome3 |
| Coordinates |
This gene maps to 50712671-51421629 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-DOCK3-04123-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-DOCK3-04123-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-DOCK3-04123-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-DOCK3-04123-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-DOCK3-04123-AQ |
467nm |
418nm |
|
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