Gene-specific Copy Number Variation Probe-DMPK
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| Catalog: |
CNVFP-DMPK-03931 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DMPK). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
DMPK Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DMPK genes. This product achieves the purpose of detection by hybridizing with the DMPK gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
DM1 Protein Kinase |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2016] |
| Gene Symbol |
DMPK |
| Location |
19q13.32 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 46272975-46285815 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-DMPK-03931-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-DMPK-03931-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-DMPK-03931-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-DMPK-03931-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-DMPK-03931-AQ |
467nm |
418nm |
|
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