Gene-specific Copy Number Variation Probe-DMP1
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Catalog: |
CNVFP-DMP1-03928 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DMP1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
DMP1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DMP1 genes. This product achieves the purpose of detection by hybridizing with the DMP1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Dentin Matrix Acidic Phosphoprotein 1 |
Gene Summary [Provided by RefSeq] |
Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
Gene Symbol |
DMP1 |
Location |
4q22.1 |
Chromosome |
Chromosome4 |
Coordinates |
This gene maps to 88571453-88585512 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-DMP1-03928-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-DMP1-03928-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-DMP1-03928-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-DMP1-03928-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-DMP1-03928-AQ |
467nm |
418nm |
|
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