Gene-specific Copy Number Variation Probe-DHCR7
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| Catalog: |
CNVFP-DHCR7-03712 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DHCR7). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
DHCR7 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DHCR7 genes. This product achieves the purpose of detection by hybridizing with the DHCR7 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
7-dehydrocholesterol Reductase |
| Gene Summary [Provided by RefSeq] |
This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009] |
| Gene Symbol |
DHCR7 |
| Location |
11q13.4 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 71145456-71159477 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-DHCR7-03712-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-DHCR7-03712-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-DHCR7-03712-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-DHCR7-03712-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-DHCR7-03712-AQ |
467nm |
418nm |
|
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