Gene-specific Copy Number Variation Probe-DFFB
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| Catalog: |
CNVFP-DFFB-03733 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DFFB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
DFFB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DFFB genes. This product achieves the purpose of detection by hybridizing with the DFFB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
DNA Fragmentation Factor Subunit Beta |
| Gene Summary [Provided by RefSeq] |
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined. [provided by RefSeq, Sep 2013] |
| Gene Symbol |
DFFB |
| Location |
1p36.32 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 3773844-3801993 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-DFFB-03733-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-DFFB-03733-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-DFFB-03733-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-DFFB-03733-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-DFFB-03733-AQ |
467nm |
418nm |
|
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