Gene-specific Copy Number Variation Probe-DDB2
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Catalog: |
CNVFP-DDB2-03539 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DDB2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
DDB2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DDB2 genes. This product achieves the purpose of detection by hybridizing with the DDB2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Damage Specific DNA Binding Protein 2 |
Gene Summary [Provided by RefSeq] |
This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
Gene Symbol |
DDB2 |
Location |
11p11.2 |
Chromosome |
Chromosome11 |
Coordinates |
This gene maps to 47236492-47260769 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-DDB2-03539-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-DDB2-03539-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-DDB2-03539-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-DDB2-03539-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-DDB2-03539-AQ |
467nm |
418nm |
|
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