Gene-specific Copy Number Variation Probe-DDB1
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| Catalog: |
CNVFP-DDB1-03541 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DDB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
DDB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DDB1 genes. This product achieves the purpose of detection by hybridizing with the DDB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Damage Specific DNA Binding Protein 1 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012] |
| Gene Symbol |
DDB1 |
| Location |
11q12.2 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 61066918-61100666 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-DDB1-03541-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-DDB1-03541-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-DDB1-03541-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-DDB1-03541-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-DDB1-03541-AQ |
467nm |
418nm |
|
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