Gene-specific Copy Number Variation Probe-DCTN1
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| Catalog: |
CNVFP-DCTN1-03552 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DCTN1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
DCTN1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DCTN1 genes. This product achieves the purpose of detection by hybridizing with the DCTN1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Dynactin Subunit 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq, Oct 2008] |
| Gene Symbol |
DCTN1 |
| Location |
2p13.1 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 74588280-74619214 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-DCTN1-03552-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-DCTN1-03552-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-DCTN1-03552-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-DCTN1-03552-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-DCTN1-03552-AQ |
467nm |
418nm |
|
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