Gene-specific Copy Number Variation Probe-DCLK1
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| Catalog: |
CNVFP-DCLK1-03572 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (DCLK1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
DCLK1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to DCLK1 genes. This product achieves the purpose of detection by hybridizing with the DCLK1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Doublecortin Like Kinase 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010] |
| Gene Symbol |
DCLK1 |
| Location |
13q13.3 |
| Chromosome |
Chromosome13 |
| Coordinates |
This gene maps to 36342788-36705514 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-DCLK1-03572-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-DCLK1-03572-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-DCLK1-03572-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-DCLK1-03572-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-DCLK1-03572-AQ |
467nm |
418nm |
|
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