Gene-specific Copy Number Variation Probe-CYP3A4
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| Catalog: |
CNVFP-CYP3A4-03685 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CYP3A4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CYP3A4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CYP3A4 genes. This product achieves the purpose of detection by hybridizing with the CYP3A4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Cytochrome P450 Family 3 Subfamily A Member 4 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011] |
| Gene Symbol |
CYP3A4 |
| Location |
7q22.1 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 99354582-99381811 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CYP3A4-03685-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CYP3A4-03685-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CYP3A4-03685-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CYP3A4-03685-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CYP3A4-03685-AQ |
467nm |
418nm |
|
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