Gene-specific Copy Number Variation Probe-CYP2D6
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| Catalog: |
CNVFP-CYP2D6-03693 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CYP2D6). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CYP2D6 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CYP2D6 genes. This product achieves the purpose of detection by hybridizing with the CYP2D6 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Cytochrome P450 Family 2 Subfamily D Member 6 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
| Gene Symbol |
CYP2D6 |
| Location |
22q13.2 |
| Chromosome |
Chromosome22 |
| Coordinates |
This gene maps to 42522500-42526883 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CYP2D6-03693-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CYP2D6-03693-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CYP2D6-03693-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CYP2D6-03693-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CYP2D6-03693-AQ |
467nm |
418nm |
|
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