Gene-specific Copy Number Variation Probe-CYBB
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Catalog: |
CNVFP-CYBB-03427 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CYBB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
CYBB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CYBB genes. This product achieves the purpose of detection by hybridizing with the CYBB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Cytochrome B-245 Beta Chain |
Gene Summary [Provided by RefSeq] |
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008] |
Gene Symbol |
CYBB |
Location |
Xp21.1-p11.4 |
Chromosome |
ChromosomeX |
Coordinates |
This gene maps to 37639269-37672714 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-CYBB-03427-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-CYBB-03427-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-CYBB-03427-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-CYBB-03427-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-CYBB-03427-AQ |
467nm |
418nm |
|
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