Gene-specific Copy Number Variation Probe-CXXC4
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| Catalog: |
CNVFP-CXXC4-03397 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CXXC4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CXXC4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CXXC4 genes. This product achieves the purpose of detection by hybridizing with the CXXC4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
CXXC Finger Protein 4 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a CXXC-type zinc finger domain-containing protein that functions as an antagonist of the canonical wingless/integrated signaling pathway. The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled, a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin. In addition, the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides, localize to promoters and CpG islands, and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2, an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA. In humans, a mutation in this gene has been associated with development of malignant renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| Gene Symbol |
CXXC4 |
| Location |
4q24 |
| Chromosome |
Chromosome4 |
| Coordinates |
This gene maps to 105393342-105412467 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CXXC4-03397-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CXXC4-03397-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CXXC4-03397-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CXXC4-03397-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CXXC4-03397-AQ |
467nm |
418nm |
|
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