Gene-specific Copy Number Variation Probe-CXCR2
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| Catalog: |
CNVFP-CXCR2-03443 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CXCR2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CXCR2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CXCR2 genes. This product achieves the purpose of detection by hybridizing with the CXCR2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
C-X-C Motif Chemokine Receptor 2 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009] |
| Gene Symbol |
CXCR2 |
| Location |
2q35 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 218990012-219001976 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CXCR2-03443-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CXCR2-03443-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CXCR2-03443-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CXCR2-03443-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CXCR2-03443-AQ |
467nm |
418nm |
|
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