Gene-specific Copy Number Variation Probe-CTSB
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Catalog: |
CNVFP-CTSB-03480 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CTSB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
CTSB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CTSB genes. This product achieves the purpose of detection by hybridizing with the CTSB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Cathepsin B |
Gene Summary [Provided by RefSeq] |
This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Nov 2015] |
Gene Symbol |
CTSB |
Location |
8p23.1 |
Chromosome |
Chromosome8 |
Coordinates |
This gene maps to 11700033-11725646 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-CTSB-03480-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-CTSB-03480-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-CTSB-03480-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-CTSB-03480-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-CTSB-03480-AQ |
467nm |
418nm |
|
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