Gene-specific Copy Number Variation Probe-CSTB
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| Catalog: |
CNVFP-CSTB-03223 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CSTB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CSTB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CSTB genes. This product achieves the purpose of detection by hybridizing with the CSTB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Cystatin B |
| Gene Summary [Provided by RefSeq] |
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies. [provided by RefSeq, Jul 2016] |
| Gene Symbol |
CSTB |
| Location |
21q22.3 |
| Chromosome |
Chromosome21 |
| Coordinates |
This gene maps to 45193830-45196259 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CSTB-03223-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CSTB-03223-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CSTB-03223-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CSTB-03223-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CSTB-03223-AQ |
467nm |
418nm |
|
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