Gene-specific Copy Number Variation Probe-CRYBB1
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| Catalog: |
CNVFP-CRYBB1-03295 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CRYBB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CRYBB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CRYBB1 genes. This product achieves the purpose of detection by hybridizing with the CRYBB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Crystallin Beta B1 |
| Gene Summary [Provided by RefSeq] |
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, undergoes extensive cleavage at its N-terminal extension during lens maturation. It is also a member of a gene cluster with beta-A4, beta-B2, and beta-B3. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
CRYBB1 |
| Location |
22q12.1 |
| Chromosome |
Chromosome22 |
| Coordinates |
This gene maps to 26995361-27013991 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CRYBB1-03295-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CRYBB1-03295-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CRYBB1-03295-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CRYBB1-03295-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CRYBB1-03295-AQ |
467nm |
418nm |
|
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