Gene-specific Copy Number Variation Probe-CRH
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| Catalog: |
CNVFP-CRH-03335 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CRH). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CRH Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CRH genes. This product achieves the purpose of detection by hybridizing with the CRH gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Corticotropin Releasing Hormone |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Nov 2015] |
| Gene Symbol |
CRH |
| Location |
8q13.1 |
| Chromosome |
Chromosome8 |
| Coordinates |
This gene maps to 67088611-67090846 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CRH-03335-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CRH-03335-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CRH-03335-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CRH-03335-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CRH-03335-AQ |
467nm |
418nm |
|
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