Gene-specific Copy Number Variation Probe-CREBL2
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| Catalog: |
CNVFP-CREBL2-03343 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CREBL2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CREBL2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CREBL2 genes. This product achieves the purpose of detection by hybridizing with the CREBL2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
CAMP Responsive Element Binding Protein Like 2 |
| Gene Summary [Provided by RefSeq] |
cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
CREBL2 |
| Location |
12p13.1 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 12764830-12798041 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CREBL2-03343-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CREBL2-03343-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CREBL2-03343-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CREBL2-03343-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CREBL2-03343-AQ |
467nm |
418nm |
|
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