Gene-specific Copy Number Variation Probe-CR1
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| Catalog: |
CNVFP-CR1-03309 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CR1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CR1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CR1 genes. This product achieves the purpose of detection by hybridizing with the CR1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Complement C3b/C4b Receptor 1 (Knops Blood Group) |
| Gene Summary [Provided by RefSeq] |
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
CR1 |
| Location |
1q32.2 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 207669472-207815110 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CR1-03309-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CR1-03309-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CR1-03309-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CR1-03309-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CR1-03309-AQ |
467nm |
418nm |
|
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