Gene-specific Copy Number Variation Probe-CPSF4
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| Catalog: |
CNVFP-CPSF4-03061 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CPSF4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CPSF4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CPSF4 genes. This product achieves the purpose of detection by hybridizing with the CPSF4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Cleavage And Polyadenylation Specific Factor 4 |
| Gene Summary [Provided by RefSeq] |
Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
CPSF4 |
| Location |
7q22.1 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 99036562-99054996 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CPSF4-03061-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CPSF4-03061-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CPSF4-03061-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CPSF4-03061-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CPSF4-03061-AQ |
467nm |
418nm |
|
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