Gene-specific Copy Number Variation Probe-COX11
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| Catalog: |
CNVFP-COX11-03051 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (COX11). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
COX11 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to COX11 genes. This product achieves the purpose of detection by hybridizing with the COX11 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
COX11, Cytochrome C Oxidase Copper Chaperone |
| Gene Summary [Provided by RefSeq] |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009] |
| Gene Symbol |
COX11 |
| Location |
17q22 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 53029258-53046064 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-COX11-03051-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-COX11-03051-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-COX11-03051-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-COX11-03051-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-COX11-03051-AQ |
467nm |
418nm |
|
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