Gene-specific Copy Number Variation Probe-COX10
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| Catalog: |
CNVFP-COX10-03049 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (COX10). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
COX10 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to COX10 genes. This product achieves the purpose of detection by hybridizing with the COX10 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
COX10, Heme A:farnesyltransferase Cytochrome C Oxidase Assembly Factor |
| Gene Summary [Provided by RefSeq] |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
COX10 |
| Location |
17p12 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 13972718-14111996 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-COX10-03049-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-COX10-03049-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-COX10-03049-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-COX10-03049-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-COX10-03049-AQ |
467nm |
418nm |
|
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