Gene-specific Copy Number Variation Probe-COL4A3
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| Catalog: |
CNVFP-COL4A3-02906 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (COL4A3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
COL4A3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to COL4A3 genes. This product achieves the purpose of detection by hybridizing with the COL4A3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Collagen Type IV Alpha 3 Chain |
| Gene Summary [Provided by RefSeq] |
Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jun 2010] |
| Gene Symbol |
COL4A3 |
| Location |
2q36.3 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 228029280-228179508 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-COL4A3-02906-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-COL4A3-02906-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-COL4A3-02906-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-COL4A3-02906-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-COL4A3-02906-AQ |
467nm |
418nm |
|
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