Gene-specific Copy Number Variation Probe-COL4A1
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Catalog: |
CNVFP-COL4A1-02910 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (COL4A1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
COL4A1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to COL4A1 genes. This product achieves the purpose of detection by hybridizing with the COL4A1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Collagen Type IV Alpha 1 Chain |
Gene Summary [Provided by RefSeq] |
This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
Gene Symbol |
COL4A1 |
Location |
13q34 |
Chromosome |
Chromosome13 |
Coordinates |
This gene maps to 110801309-110959496 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-COL4A1-02910-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-COL4A1-02910-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-COL4A1-02910-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-COL4A1-02910-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-COL4A1-02910-AQ |
467nm |
418nm |
|
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