Gene-specific Copy Number Variation Probe-CLPB
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Catalog: |
CNVFP-CLPB-02962 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CLPB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
CLPB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CLPB genes. This product achieves the purpose of detection by hybridizing with the CLPB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
ClpB Homolog, Mitochondrial AAA ATPase Chaperonin |
Gene Summary [Provided by RefSeq] |
This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
Gene Symbol |
CLPB |
Location |
11q13.4 |
Chromosome |
Chromosome11 |
Coordinates |
This gene maps to 72003469-72145568 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-CLPB-02962-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-CLPB-02962-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-CLPB-02962-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-CLPB-02962-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-CLPB-02962-AQ |
467nm |
418nm |
|
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