Gene-specific Copy Number Variation Probe-CLDN16
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| Catalog: |
CNVFP-CLDN16-02765 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CLDN16). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CLDN16 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CLDN16 genes. This product achieves the purpose of detection by hybridizing with the CLDN16 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Claudin 16 |
| Gene Summary [Provided by RefSeq] |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28. [provided by RefSeq, Jun 2010] |
| Gene Symbol |
CLDN16 |
| Location |
3q28 |
| Chromosome |
Chromosome3 |
| Coordinates |
This gene maps to 190105660-190129932 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CLDN16-02765-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CLDN16-02765-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CLDN16-02765-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CLDN16-02765-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CLDN16-02765-AQ |
467nm |
418nm |
|
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