Gene-specific Copy Number Variation Probe-CLCN3
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Catalog: |
CNVFP-CLCN3-02772 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CLCN3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
CLCN3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CLCN3 genes. This product achieves the purpose of detection by hybridizing with the CLCN3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Chloride Voltage-gated Channel 3 |
Gene Summary [Provided by RefSeq] |
This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
Gene Symbol |
CLCN3 |
Location |
4q33 |
Chromosome |
Chromosome4 |
Coordinates |
This gene maps to 170541671-170644338 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-CLCN3-02772-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-CLCN3-02772-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-CLCN3-02772-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-CLCN3-02772-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-CLCN3-02772-AQ |
467nm |
418nm |
|
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