Gene-specific Copy Number Variation Probe-CIITA
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| Catalog: |
CNVFP-CIITA-02809 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CIITA). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CIITA Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CIITA genes. This product achieves the purpose of detection by hybridizing with the CIITA gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Class II Major Histocompatibility Complex Transactivator |
| Gene Summary [Provided by RefSeq] |
This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the "master control factor" for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
| Gene Symbol |
CIITA |
| Location |
16p13.13 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 10971054-11018840 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CIITA-02809-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CIITA-02809-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CIITA-02809-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CIITA-02809-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CIITA-02809-AQ |
467nm |
418nm |
|
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