Gene-specific Copy Number Variation Probe-CIC
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| Catalog: |
CNVFP-CIC-02814 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CIC). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CIC Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CIC genes. This product achieves the purpose of detection by hybridizing with the CIC gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Capicua Transcriptional Repressor |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG)-box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C-terminus. Studies suggest that the N-terminal region of this protein interacts with Atxn1 (GeneID:6310), to form a transcription repressor complex, and in vitro studies suggest that polyglutamine-expansion of ATXN1 may alter the repressor activity of this complex. Mutations in this gene have been associated with olidogdendrogliomas (PMID:21817013). In addition, translocation events resulting in gene fusions of this gene with both DUX4 (GeneID:100288687) and FOXO4 (GeneID:4303) have been associated with round cell sarcomas. There are multiple pseudogenes of this gene found on chromosomes 1, 4, 6, 7, 16, 20, and the Y chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2015] |
| Gene Symbol |
CIC |
| Location |
19q13.2 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 42788816-42799949 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CIC-02814-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CIC-02814-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CIC-02814-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CIC-02814-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CIC-02814-AQ |
467nm |
418nm |
|
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