Gene-specific Copy Number Variation Probe-CHRNB3
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| Catalog: |
CNVFP-CHRNB3-02827 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CHRNB3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CHRNB3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CHRNB3 genes. This product achieves the purpose of detection by hybridizing with the CHRNB3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Cholinergic Receptor Nicotinic Beta 3 Subunit |
| Gene Summary [Provided by RefSeq] |
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region.[supplied by OMIM, Apr 2010] |
| Gene Symbol |
CHRNB3 |
| Location |
8p11.21 |
| Chromosome |
Chromosome8 |
| Coordinates |
This gene maps to 42552561-42592209 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CHRNB3-02827-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CHRNB3-02827-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CHRNB3-02827-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CHRNB3-02827-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CHRNB3-02827-AQ |
467nm |
418nm |
|
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