Gene-specific Copy Number Variation Probe-CHRNA2
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Catalog: |
CNVFP-CHRNA2-02834 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CHRNA2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
CHRNA2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CHRNA2 genes. This product achieves the purpose of detection by hybridizing with the CHRNA2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Cholinergic Receptor Nicotinic Alpha 2 Subunit |
Gene Summary [Provided by RefSeq] |
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009] |
Gene Symbol |
CHRNA2 |
Location |
8p21.2 |
Chromosome |
Chromosome8 |
Coordinates |
This gene maps to 27317277-27336813 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-CHRNA2-02834-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-CHRNA2-02834-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-CHRNA2-02834-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-CHRNA2-02834-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-CHRNA2-02834-AQ |
467nm |
418nm |
|
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