Gene-specific Copy Number Variation Probe-CHCHD2
Add to Cart
| Catalog: |
CNVFP-CHCHD2-02627 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CHCHD2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CHCHD2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CHCHD2 genes. This product achieves the purpose of detection by hybridizing with the CHCHD2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Coiled-coil-helix-coiled-coil-helix Domain Containing 2 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to a class of eukaryotic CX(9)C proteins characterized by four cysteine residues spaced ten amino acids apart from one another. These residues form disulfide linkages that define a CHCH fold. In response to stress, the protein translocates from the mitochondrial intermembrane space to the nucleus where it binds to a highly conserved 13 nucleotide oxygen responsive element in the promoter of cytochrome oxidase 4I2, a subunit of the terminal enzyme of the electron transport chain. In concert with recombination signal sequence-binding protein J, binding of this protein activates the oxygen responsive element at four percent oxygen. In addition, it has been shown that this protein is a negative regulator of mitochondria-mediated apoptosis. In response to apoptotic stimuli, mitochondrial levels of this protein decrease, allowing BCL2-associated X protein to oligomerize and activate the caspase cascade. Pseudogenes of this gene are found on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| Gene Symbol |
CHCHD2 |
| Location |
7p11.2 |
| Chromosome |
Chromosome7 |
| Coordinates |
This gene maps to 56169265-56174187 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CHCHD2-02627-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CHCHD2-02627-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CHCHD2-02627-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CHCHD2-02627-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CHCHD2-02627-AQ |
467nm |
418nm |
|
Other Products
