Gene-specific Copy Number Variation Probe-CFI
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| Catalog: |
CNVFP-CFI-02575 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CFI). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CFI Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CFI genes. This product achieves the purpose of detection by hybridizing with the CFI gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Complement Factor I |
| Gene Summary [Provided by RefSeq] |
This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene. [provided by RefSeq, Dec 2015] |
| Gene Symbol |
CFI |
| Location |
4q25 |
| Chromosome |
Chromosome4 |
| Coordinates |
This gene maps to 110661847-110723335 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CFI-02575-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CFI-02575-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CFI-02575-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CFI-02575-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CFI-02575-AQ |
467nm |
418nm |
|
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