Gene-specific Copy Number Variation Probe-CFB
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| Catalog: |
CNVFP-CFB-02661 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CFB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CFB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CFB genes. This product achieves the purpose of detection by hybridizing with the CFB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Complement Factor B |
| Gene Summary [Provided by RefSeq] |
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
CFB |
| Location |
6p21.33 |
| Chromosome |
Chromosome6_dbb_hap3 |
| Coordinates |
This gene maps to 3199308-3205449 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CFB-02661-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CFB-02661-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CFB-02661-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CFB-02661-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CFB-02661-AQ |
467nm |
418nm |
|
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