Gene-specific Copy Number Variation Probe-CEP57
Add to Cart
| Catalog: |
CNVFP-CEP57-02404 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (CEP57). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
CEP57 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to CEP57 genes. This product achieves the purpose of detection by hybridizing with the CEP57 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Centrosomal Protein 57 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
| Gene Symbol |
CEP57 |
| Location |
11q21 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 95523624-95565857 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-CEP57-02404-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-CEP57-02404-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-CEP57-02404-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-CEP57-02404-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-CEP57-02404-AQ |
467nm |
418nm |
|
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